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Corel Medical Series: Cancer
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c11a.dxr
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00056_Field_SRC.c11a.A.4.txt
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1997-01-31
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At Significantly Higher Risk
• Advancing age, usually over age 40.
• Family history of colorectal cancer, especially among first-degree relatives (Lynch syndrome Type I). The risk
is two to three times the risk of an average person.
• "Cancer Family Syndrome" (Lynch syndrome Type II), with a higher risk for colon cancer and other
adenocarcinomas such as cancers of the ovary, endometrium, breast and pancreas.
• A personal or family history of multiple adenomatous polyps after age 10 (familial polyposis).
• Previous polyps of the colon and rectum.
• Inflammatory bowel disease such as ulcerative colitis and ileitis (Crohn's disease). With ulcerative colitis, the
risk of cancer is about 20 times the average. Cancer may also develop in the flat surface of the mucosa rather
than in polyps. Increased risk for ulcerative colitis occurs in gynecologic cancer, prostate or pelvic cancer, and
pelvic cancer following radiation therapy .
• Diets high in fat and low in fiber and calcium . Animal rather than vegetable fat is believed responsible. One
study indicated that women eating red meat (beef, lamb and pork) daily had 2 1/2 times the risk of those who
eat red meat less than once a month. Those eating fish and chicken without the skin were at lesser risk.
• High consumption of charcoal-broiled foods.
• Inactivity and constipation.
• Asbestos exposure.
• European (Ashkenazy) Jews.